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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Andrea Bucceri
Welcome to BMC Chemical Biology published by BioMed Central
BMC Chemical Biology is an open access journal publishing original peer-reviewed research articles in the application of chemistry to the investigation of biology and drug design.
BMC Chemical Biology (ISSN 1472-6769) is indexed/tracked/covered by PubMed, BIOSIS, CAS, Scopus, EMBASE and Google Scholar.
BMC Chemical Biology 2008, 8 :3
The analysis of separate components of cellular growth dynamics allows a sophisticated assessment of the effect of drug-drug and drug-gene interactions upon cells, and may help characterize the physiological impact of orphan bioactive compounds.
BMC Chemical Biology 2008, 8 :2
Inducing apoptosis using compounds screened from a chemical library demonstrates that calcium signaling is generally not an early event and suggests that the calmodulin kinase II pathway is often important in sustaining apoptosis.
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Research article
Chemogenetic fingerprinting by analysis of cellular growth dynamics Jonas Warringer, Dragi Anevski, Beidong Liu, Anders Blomberg BMC Chemical Biology 2008, 8 :3 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Charting calcium-regulated apoptosis pathways using chemical biology: role of calmodulin kinase II Maria H BMC Chemical Biology 2008, 8 :2 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Identification of cellular pathways affected by Sortin2, a synthetic compound that affects protein targeting to the vacuole in Saccharomyces cerevisiae Lorena Norambuena, Jan Zouhar, Glenn R Hicks, Natasha V Raikhel BMC Chemical Biology 2008, 8 :1 (7 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Enhancement of intracellular Yuichiro Tanaka, Leslie A Lesoon Wood, Robert V Cooney BMC Chemical Biology 2007, 7 :2 (3 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
The effect of amino acid deletions and substitutions in the longest loop of GFP Gabriela Flores-Ram BMC Chemical Biology 2007, 7 :1 (26 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Studies on the synthesis, characterization, binding with DNA and activities of two cis -planaramineplatinum(II) complexes of the form: cis -PtL(NH3 )Cl2 where L = 3-hydroxypyridine and 2,3-diaminopyridine Ahmed Abdullah, Fazlul Huq, Ashraf Chowdhury, Hasan Tayyem, Philip Beale, Keith Fisher BMC Chemical Biology 2006, 6 :3 (13 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Small-molecule and mutational analysis of allosteric Eg5 inhibition by monastrol Zoltan Maliga, Timothy J Mitchison BMC Chemical Biology 2006, 6 :2 (27 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Uncharged isocoumarin-based inhibitors of urokinase-type plasminogen activator Justin J Heynekamp, Lucy A Hunsaker, Thomas A Vander Jagt, Lorraine M Deck, David L Vander Jagt BMC Chemical Biology 2006, 6 :1 (8 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Covalent attachment of the plant natural product naringenin to small glass and ceramic beads Yuhua Lu, Niloufer G Irani, Erich Grotewold BMC Chemical Biology 2005, 5 :3 (10 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Electronic properties of amino acid side chains: quantum mechanics calculation of substituent effects Donard S Dwyer BMC Chemical Biology 2005, 5 :2 (3 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Differential solubility of curcuminoids in serum and albumin solutions: implications for analytical and therapeutic applications Wolfgang W Quitschke BMC Biotechnology 2008, 8 :84 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Quantification of gamma-secretase modulation differentiates inhibitor compound selectivity between two substrates Notch and amyloid precursor protein Ting Yang, Dilyara Arslanova, Yongli Gu, Corinne Augelli-Szafran, Weiming Xia Molecular Brain 2008, 1 :15 (4 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid Dae-Kyun Ro, Mario Ouellet, Eric M. Paradise, Helcio Burd, Diana Eng, Chris J. Paddon, Jack D. Newman, Jay D. Keasling BMC Biotechnology 2008, 8 :83 (4 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
In silico analysis of methyltransferase domains involved in biosynthesis of secondary metabolites Mohd. Zeeshan Ansari, Jyoti Sharma, Rajesh S Gokhale, Debasisa Mohanty BMC Bioinformatics 2008, 9 :454 (25 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Gamma-secretase inhibition combined with platinum compounds enhances cell death in a large subset of colorectal cancer cells Tamara Aleksic, Stephan M Feller Cell Communication and Signaling 2008, 6 :8 (24 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research
Enhanced A3 adenosine receptor selectivity of multivalent nucleoside-dendrimer conjugates Athena M Klutz, Zhan-Guo Gao, John Lloyd, Asher Shainberg, Kenneth A Jacobson Journal of Nanobiotechnology 2008, 6 :12 (23 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research
A role of p38 mitogen-activated protein kinase in adenosine A1 receptor-mediated synaptic depotentiation in area CA1 of the rat hippocampus Ying-Ching Liang, Chiung-Chun Huang, Kuei-Sen Hsu Molecular Brain 2008, 1 :13 (23 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Short report
Haemostasis and ageing Daniela Mari, Giulia Ogliari, Davide Castaldi, Giovanni Vitale, Elisa M Bollini, Domenico Lio Immunity & Ageing 2008, 5 :12 (23 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Software
Envelope: interactive software for modeling and fitting complex isotope distributions Michael T Sykes, James R Williamson BMC Bioinformatics 2008, 9 :446 (20 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Case Report
Survival in a patient with severe paraneoplastic hyponatremia: a case report Gary V Walker, Michael C Peterson Cases Journal 2008, 1 :248 (17 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
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